【基本情況】
助理研究員,專業方向為分子藥理學。
聯系方式:ltian0875@163.com
【目前承擔課程】
專業必修課——毒理學基礎;
通識模塊課程——生活中的微生物與健康,Biosafety Training and Environmental Health Safety等。
【主要科研成果】
研究領域主要涉及信号轉導通路研究,疾病(主要是抑郁症等神經精神類疾病)的發生機理和生物标記物探索,主持和參與省部級以及國家級科研課題數項,在國内外期刊發表文章十餘篇。
一、代表性課題有:
四川省衛計委重點研究項目,GRK5多态性在糖尿病易感性和糖代謝關鍵信号通路中的作用,2016-2018,(16ZD023)。
中國自然科學基金,載脂蛋白ApoA-I模拟多肽D-4F對塵肺纖維化的作用及機理研究,2015/01-2017/12,(81402642)。
中國自然科學基金,天然多酚白藜蘆醇對塵肺肺纖維化的作用及機制研究,2016/01-2018/12,(81502768)。
四川省科技廳,多酚類天然産物對塵肺纖維化的作用及機制研究(2015JY0212)。
二、代表性論著見下:
Weihong Kuang, Mingyue Gao,Liantian Tian, Yang Wan, Peiyuan Qiu. Trends in the prevalence of cognitive impairment in Chinese older adults: based on the Chinese Longitudinal Healthy Longevity Survey cohorts from 1998 to 2014.Int Health. 2020,12: 378-387.
Weihong Kuang, Zaiquan Dong,Liantian Tian, Jin Li. MicroRNA-451a, microRNA-34a-5p, and microRNA221-3p as predictors of response to antidepressant treatment.Braz J Med Biol Res. 2018, 51(7): e7212.
Jingyuan Xiong,Liantian Tian, Yongjie Qiu, Ding Sun, Hao Zhang, Mei Wu, Jintao Wang. Evaluation on the thyroid disrupting mechanism of malathion in Fischer rat thyroid follicular cell line FRTL-5.Drug Chem Toxicol. 2018, 41(4): 501-508.
Weihong Kuang,Liantian Tian, Lili Yue, Jin Li. Effects of Escitalopram with a Chinese traditional compound Jiuweizhenxin-keli on MMN and P50 of patients with Major Depressive Disorder,Neuropsychiatr Dis Treat. 2016, 2016: 1935-41.
Jiayi Chen, Yuqin Yao, Xiaolan Su, Ying Shi, Xuejiao Song, Linshen Xie, Jia You,LiantianTian, Luo Yang, Aiping Fang, Jingyuan Xiong. Comparative RNA-Seq transcriptome analysis on silica induced pulmonary inflammation and fibrosis in mice silicosis model.J. Appl. Toxicol. 2018, 38: 773-782.
Weihong Kuang, Zaiquan Dong,Liantian Tian, Jin Li. IGF-1 Defends Against Chronic-Stress Induced Depression in Rat Models of Chronic Unpredictable Mild Stress Through the PI3K/Akt/FoxO3a Pathway.Kaohsiung J Med Sci.2018, 34(7): 370-376.
Yu Liu, Haojiang Zuo, Yao Wang,Liantian Tian, Xin Xu, Jingyuan Xiong, Xiaofang Pei. Ethanol promotes apoptosis in rat ovarian granulosa cells via the Bcl-2 family dependent intrinsic apoptotic pathway.Cell Mol Biol (Noisy-le-grand). 2018, 64(1): 118-125.
YanxiaWu, JingyuanXiong,LiantianTian, XiaofangPei, Yunrong Chai. Microbial Persisters and Health Care.Modern Preventive Medicine, 2014, 41(05): 908-910.
Yirong Li,Liantian Tian, Martin Ligr, Daniels Garrett, Peng Yi, Xinyu Wu, Singh Mandeep, Jianjun Wei, Yongzhao Shao, Lepor Herbert, Ruliang Xu, Zhijie Chang, Zhengxin Wang, Peng Lee. Functional Domains of Androgen Receptor Coactivator p44/Mep50/WDR77 and its Interaction with Smad1.PLoSONE. 2013, 8(5):e64663.
Martin Ligr, Patwa Ruzeen Rohintan, Daniels Garrett, Pan Lorraine, Xinyu Wu, Yirong Li,Liantian Tian, Zhenxing Wang, Ruliang Xu, Jingjing Wu, Fan Chen, Jinsong Liu, Jianjun Wei, Peng Lee. Expression and Function of Androgen Receptor Coactivator p44/Mep50 in Ovarian Cancer.PLoS ONE. 2011, 6(10): e26250.
LiantianTianand Kammermeier Paul J.G protein coupling profile of mGluR6 and expression of G alpha proteins in retinal ON bipolar cells.Visual Neuroscience.2006, 23(6): 909-16.
【獲獎情況】
2019年度澳门新葡萄新京威尼斯通識模塊課程最受歡迎教師。
Kent State University Graduate Student Research Grant, Kent State University, Kent, OH, 2008.
Outstanding Poster Award, Research Conference of the School of Biomedical Sciences, Kent State University, Kent, OH, 2008.
Frank G. Standaert Award, The American Society for Pharmacology and Experimental Therapeutics, Annual Meeting at Experimental Biology 2008, San Diego, CA, 2008.
Postdoctoral Prostate Cancer Training Award, Department of Defense, 2010.