【基本情況】
姜俠，研究員，博士生導師，營養與食品衛生學系主任。畢業于浙江大學和瑞典卡羅林斯卡醫學院，獲得學士、碩士和博士學位。曾任哈佛大學和卡羅林斯卡醫學院博士後、助理研究員以及助理教授。四川省醫學會專科高級會員、丁香醫生健康百科知識工程首批專家會員、Frontiers in Genetics雜志客座編輯、《現代預防醫學》雜志編委。入選四川省高層次人才計劃以及澳门新葡萄新京威尼斯“雙百人才工程”。
姜俠博士長期緻力于慢性複雜疾病的遺傳流行病學研究，并在自身免疫疾病領域取得突出成績，通過精細定位基因-環境交互作用、構建疾病風險預測模型、探索疾病精準分型并使用系統流行病學方法解析慢性非傳染性疾病的複雜病因網絡，完成系列代表性工作。
截至2022年12月，總共發表SCI論文84篇（總引用大于4200次、單篇最高他引1032次、H指數27）；其中以第一或通訊作者（含共同）在Annals of Rheumatic Diseases(IF=28.0)、Nature Communications (IF=17.7)、Arthritis Rheumatology (IF=15.5)、BMC medicine (IF=11.2)、American Journal of Human Genetics (IF=11.0)、Diabetologia (IF=10.5)、International Journal of Epidemiology (IF=9.7)等期刊發表高水平論文49篇（總引用大于1300次、單篇最高他引284次）。以負責人身份獲海外經費約1800萬人民币。
電子郵箱：xiajiang@scu.edu.cn
【目前承擔課程】
《營養流行病學》（本科生）
《預防醫學與公共衛生的“服務學習”實踐》（本科生）
《營養與健康》（研究生）
《醫學營養學》（研究生）
《群醫學》（研究生）
【主要科研成果】
主要科研項目：
四川省醫學會：中國西南區域兒童青少年睡眠的遺傳易感機制研究
四川省科技廳：四川省“天府峨眉計劃”青年人才項目
國家自然科學基金青年項目：遺傳預測的體力活動與青少年抑郁的分子流行病學研究
近五年（2018-2022）代表性論文（高水平SCI雜志；#貢獻相同，*通訊作者）
Tang B, Liu Q, Ilar A, Wiebert, P, Hägg, S, Padyukov, L, Klareskog, L, Alfredsson, L,Jiang, X*. Occupational inhalable agents constitute major risk factors for rheumatoid arthritis, particularly in the context of genetic predisposition and smoking.Ann Rheum Dis. 2022 Dec ard-2022-223134.
Xin J#,Jiang X#, Ben S, Yuan Q, Su L, Zhang Z, Christiani DC, Du M, Wang M. Association between circulating vitamin E and ten common cancers: evidence from large-scale Mendelian randomization analysis and a longitudinal cohort study. BMC Med. 2022 May 11;20(1):168.
Liu Q, Zhu Z, Kraft P, Deng Q, Stener-Victorin E,Jiang X*. Genomic correlation, shared loci, and causal relationship between obesity and polycystic ovary syndrome: a large-scale genome-wide cross-trait analysis. BMC Med. 2022 Feb 11;20(1):66.
Hao Y, Xiao J, Liang Y, Wu X, Zhang H, Xiao C, Zhang L, Burgess S, Wang N, Zhao X, Kraft P, Li J,Jiang X*. Reassessing the causal role of obesity in breast cancer susceptibility: a comprehensive multivariable Mendelian randomization investigating the distribution and timing of exposure. Int J Epidemiol. 2022 Jul 15:dyac143.
Wu X, Xiao C, Han Z, Zhang L, Zhao X, Hao Y, Xiao J, Gallagher CS, Kraft P, Morton CC, Li J,Jiang X*. Investigating the shared genetic architecture of uterine leiomyoma and breast cancer: a genome-wide cross-trait analysis. Am J Hum Genet. 2022 Jul 7;109(7):1272-1285.
Liu Q, Tang B, Zhu Z, Kraft P, Deng Q, Stener-Victorin E,Jiang X*. A genome-wide cross-trait analysis identifies shared loci and causal relationships of type 2 diabetes and glycaemic traits with polycystic ovary syndrome. Diabetologia. 2022 Sep;65(9):1483-1494.
Liu H, Xin J, Cai S,Jiang X*. Mendelian randomization analysis provides causality of smoking on the expression of ACE2, a putative SARS-CoV-2 receptor. Elife. 2021 Jul 6;10:e64188.
Huang H, Zhou J, Chen H, Li J, Zhang C,Jiang X*, Ni C. The immunomodulatory effects of endocrine therapy in breast cancer. J Exp Clin Cancer Res. 2021 Jan 7;40(1):19.
Tang B, Shi H, Alfredsson L, Klareskog L, Padyukov L,Jiang X*. Obesity-related traits and the development of rheumatoid arthritis: evidence from genetic data. Arthritis Rheumatol. 2021 Feb;73(2):203-211.
Xin J#, Du M#,Jiang X#, Wu Y, Ben S, Zheng R, Chu H, Li S, Zhang Z, Wang M. Systematic evaluation of the effects of genetic variants on PIWI-interacting RNA expression across 33 cancer types. Nucleic Acids Res. 2021 Jan 11;49(1):90-97.
Jiang X#, Dimou NL#, Al-Dabhani K, Lewis SJ, Martin RM, Haycock PC, Gunter MJ, Key TJ, Eeles RA, Muir K, Neal D, Giles GG, Giovannucci EL, Stampfer M, Pierce BL, Schildkraut JM, Warren Andersen S, Thompson D, Zheng W, Kraft P, Tsilidis KK; PRACTICAL, CRUK, BPC3, CAPS and PEGASUS consortia. Circulating vitamin D concentrations and risk of breast and prostate cancer: a Mendelian randomization study. Int J Epidemiol. 2019 Oct 1;48(5):1416-1424.
Jiang X, Finucane HK, Schumacher FR, …, Amos CI, Kraft P, Lindström S. Shared heritability and functional enrichment across six solid cancers. Nat Commun. 2019 Jan 25;10(1):431.
Zeng P, Chen Z, Klareskog L, Alfredsson L, Bengtsson C,Jiang X*. Amount of smoking, duration of smoking cessation and their interaction with silica exposure in the risk of rheumatoid arthritis among males: results from the Swedish Epidemiological Investigation of Rheumatoid Arthritis (EIRA) study. Ann Rheum Dis. 2018 Aug;77(8):1238-1241.
Jiang X#, O’Reilly PF#, Aschard H, …, Hyppönen E, Kraft P, Kiel DP. Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. Nat Commun. 2018 Jan 17;9(1):260.
全部論文請見：https://scholar.google.com/citations?hl=en&user=DYYozXAAAAAJ
