四川省中華預防醫學會環境衛生分會常委;四川省預防醫學學會環境衛生分委會主任委員;中國醫院建設及裝備協會醫院水系統學組專家;四川省環境科學學會理事,四川省成都市環境學會主任委員。《澳门新葡萄新京威尼斯學報(醫學版)》、《環境衛生學雜志》、《中國食品衛生雜志》編委,《預防醫學情報雜志》副主編。
作為負責人主持過6個國家自然科學基金項目,多個四川省科技廳和成都市科技局科研項目;發表科研論文近300篇,其中60多篇發表在國際環境科學、毒理學、藥理學類主流期刊,具有較好影響力。參編過《環境衛生學》、《現代環境衛生學》、《中華醫學百科全書環境衛生學》等教科書、教輔書的章節。
Donglei Sun, Chao Zuo, Wei Huang, Jingjing Wang, Zunzhen Zhang, Triclosan targeting of gut microbiome ameliorates hepatic steatosis in high fat diet-fed mice, The Journal of Antibiotics,2022,https://doi.org/10.1038/s41429-022-00522-w,
王婷,孫東雷,趙田禾,張遵真.中國直飲水及相關衛生标準比較分析,澳门新葡萄新京威尼斯學報(醫學版),2021,52(5):729-734。
Ting Wang, Donglei Sun, Qian Zhang, Zunzhen Zhang*.China's drinking water sanitation from 2007 to 2018: A systematic review. Science of the Total Environment, 2121,757:143923.
Donglei Sun, Tianhe Zhao, Keyan Long, Mei Wu, Zunzhen Zhang. Triclosan down-regulates fatty acid synthase through microRNAs in HepG2 cells, European Journal of Pharmacology,2021;907:174261...
左超,孫東雷,王靜靜,黃維,張遵真,三氯生改善非酒精性脂肪性肝病小鼠的肝髒脂肪沉積,現代預防醫學,2021.48:22,4176-4180
Tianhe Zhao, Donglei Sun, Manyu Zhao,Yanhao Lai, Yuan Liu,and Zunzhen Zhang.N6-methyladenosine mediates arsenite-induced human keratinocyte transformation by suppressing p53activation. Environmental pollution,2020,259:113908,
Donglei Sun, Tianhe Zhao, Ting Wang, Mei Wu and Zunzhen Zhang. Genotoxicity assessment of triclocarban by comet and micronucleus assays and Ames test. Environmental science and pollution research.2020, 27:7430-7438
Xinyang Li, Donglei Sun, Tianhe Zhao, Zunzhen Zhang. Long non coding RNA ROR confers arsenic trioxide resistance to HepG2 cells by inhibiting p53 expression. European journal of pharmacology, 2020,872:172982
Xinyang Li, Zuo Chao, Donglei Sun, Tianhe Zhao, Zunzhen Zhang. Arsenite increases Linc-ROR in human bronchial epithelial cells that can be inhibited by antioxidant factors. Biological trace element research,2020 ;198(1):131-141.
Xinyang Li, Zuo Chao, Mei Wu, Zunzhen Zhang. Linc-ROR promotes arsenite-transformed keratinocyte proliferation by inhibiting P53 activity. metallomics, 2020, 12, 963-973.
Donglei Sun, Tianhe Zhao, Qian Zhang, Mei Wu, and Zunzhen Zhang.Fat mass and obesity-associated protein regulates lipogenesis via m6A modification in fatty acid synthase mRNA. Cell Biol Int., 2020;1-11.
Hongyu Chen, Tianhe Zhao, Donglei Sun, Mei Wu, Zunzhen Zhang. Changes of RNA N6-methyladenosine in the hormesis effect induced by arsenite on human keratinocyte cells. Toxicology in vitro, 2019,56:84-92.
Tianhe Zhao, Xinyang Li, Donglei Sun, Zunzhen Zhang.Oxidative stress: One potential factor for arsenite-induced increase of N6-methyladenosine in human keratinocytes. Environmental Toxicology and Pharmacology, 2019,69:95-103.
Donglei Sun, Tianhe Zhao, Xinyang Li & Zunzhen Zhang. Evaluation of DNA and chromosomal damage in two human HaCaT and L02 cells treated with varying triclosan concentrations. Journal of Toxicology and Environmental Health, Part A Current Issues. 2019;82(7):473-482
Donglei Sun, Tianhe Zhao, Ting Wang, Mei Wu and Zunzhen ZhangGenotoxicity assessment of triclocarban by comet and micronucleus assays and Ames test.Environmental science and pollution research.2019, 12yue online,DOI/org/10.1007/sii356-019-07351-9
Shiyan Gu, Donglei Sun, Huangmei Dai, Zunzhen Zhang.N6-methyladenosine mediates the cellular proliferation and apoptosis via microRNAs in arsenite-transformed cells. Toxicology Letters, 2018,292:1-11.
Shiyan Gu, Donglei Sun, Xinyang Li, Zunzhen Zhang. Alterations of miRNAs and their potential roles in arsenite-induced transformation of human bronchial epithelial cells. Genes (Basel) , 2017, 8(10): E254.
Shiyan Gu, Yanhao Lai, Hongyu Chen, Yuan Liu, Zunzhen Zhang. miR-155 mediates arsenic trioxide resistance by activating Nrf2 and suppressing apoptosis in lung cancer cells. Sci Rep. 2017, 7(1): 12155.
Chengzhi Chen, Xuejun Jiang, Shiyan Gu, Zunzhen Zhang. MicroRNA-155 regulates arsenite-induced malignant transformation by targeting Nrf2-mediated oxidative damage in human bronchial epithelial cells. Toxicology Letters, 2017, 278: 38-47.
Tianhe Zhao; Lichun Wu; Xinyang Li, Huangmei Dai and Zunzhen Zhang._Large intergenic non-coding RNA-ROR as a potential biomarker for the diagnosis and dynamic monitoring of breast cancer. Cancer Biomarkers, 2017, 20:165-173.
Qingyin Luo, Jill M. Beaver, Yuan Liu and Zunzhen Zhang. Dynamics of p53: A Master Decider of Cell Fate. Genes, 2017, 2017 Feb 9;8(2), pii: E66.
Hongyu Chen, Shiyan Gu, Huangmei Dai, Xinyang Li, Zunzhen Zhang, Dihydroartemisinin Sensitizes Human Lung Adenocarcinoma A549 Cells to Arsenic Trioxide via Apoptosis. Biol Trace Elem Res, 2017,179(2)203-212.
Xuejun Jianga, Chengzhi Chena, Shiyan Gu, Zunzhen Zhang, Regulation of ABCG2 by nuclear factor kappa B affects the sensitivity of human lung adenocarcinoma A549 cells to arsenic trioxide. Environmental Toxicology and Pharmacology,2018,57: 141–150
Chengzhi Chen, Shiyan Gu, Xuejun Jiang, Zunzhen Zhang. Nuclear translocation of nuclear factor kappa B is regulated by G protein signaling pathway in arsenite-induced apoptosis in HBE cell line. Environ Toxicol. 2016, 31(12):1819-1833.
Shiyan Gu, Chengzhi Chen, Xuejun Jiang, Zunzhen Zhang. ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction underlie apoptosis induced by resveratrol and arsenic trioxide in A549 cells. Chem Biol Interact. 2016,245,100-109.
Chengzhi Chen, Shiyan Gu, Xuejun Jiang, Zunzhen Zhang,Arsenite-Induced Endoplasmic Reticulum-Dependent Apoptosis Through Disturbance of Calcium Homeostasis in HBE Cell Line,Environmental Toxicology,2017,32:197-216.
Chengzhi Chen, Xuejun Jiang, Shiyan Gu, Yanhao Lai, Yuan Liu, Zunzhen Zhang. Protection of Nrf2 Against Arsenite-induced Oxidative Damage is Regulated by the Cyclic Guanosine Monophosphate-Protein Kinase G Signaling Pathway. Environmental Toxicology,Environ Toxicol. 2017, 32(8):2004-2020.